
“Doctors Claim HIV-Positive Man Cured by Stem Cell Transplant” – Fox News: December 14, 2010
“Stem Cell Transplant cures HIV in ‘Berlin Patient’”- Huffington Post: December 14, 2010
“Evidence for the cure of HIV infection”- Blood: March 10, 2011
Beginning in 2009, rumors suggesting the discovery of a miraculous “cure for HIV” made their way to major news publications and scientific journals throughout the world. The exciting news revolves around Timothy Ray Brown, a forty year old resident of Berlin infected with both HIV and leukemia. Dubbed the “Berlin patient,” Brown received a stem cell transplant in 2007 to treat his leukemia. The cells he received lacked a key piece that HIV needs to infect cells- a molecule called CCR5. The result was astounding: follow up tests could not detect any active HIV in his blood. Over three years later, they still can’t! Finally, after 30 long years the world has found a cure for the treacherous HIV virus that has killed over 25 million people! Right?
Well…not quite. Before calling the Berlin patient’s treatment a cure for HIV, it is important to know that there are two different ways to use the word cure:
- Cure (as a verb): To relieve one of the symptoms of a disease or condition
- Cure (as a noun): A complete or permanent solution or remedy
These two definitions actually make a difference in understanding what we can say about the Berlin patient. Using the verb form, we can say that the Berlin patient was “cured” of HIV because eliminating of the virus from his body relieved him of the infection. However, I don’t believe we can use the noun form to call stem cell treatment a “cure” for HIV because it is not a permanent solution to the HIV epidemic.
Firstly, the stem cell transplant Timothy Brown received is not simple and in fact, it can be deadly. The procedure involved taking special blood cells from a donor who is resistant to HIV and putting them into his own HIV infected blood. There are many dangers involved with this type of treatment, most notably the risk of transplanted stem cells recognizing the recipient’s body as foreign and attacking it. This process is extremely harmful to the recipient and can be fatal. Read more of this post
37.775667
-122.419608